{
 "paper": "kolb-2026-igabasnfr2",
 "adjudicated": "2026-09-11",
 "by": "supplied:runs/kolb-2026-igabasnfr2/adjudication.answer.json",
 "note": "Verdicts for spans the mechanical match could not resolve. covered = a claim does account for it; gap = a real hole; not-an-assertion = the span states no result of its own. Every verdict carries `sha`, the fingerprint of the sentence it judged. A `gap` also carries `tree`, the fingerprint of which claims existed when it was judged, and a `covered` carries `claim_sha`, the wording of the claim it named — because a gap is a statement about the tree, and closing one is exactly the edit that used to leave the verdict standing over nothing. `coverage` discards a verdict whose fingerprints no longer match rather than applying a judgement nobody made about what is there now.",
 "spans": [
  {
   "uid": "results-001",
   "verdict": "gap",
   "claim": null,
   "why": "The tree never states what iGABASnFR1 was engineered to do or how it performed, so this baseline characterisation of the predecessor sensor rests on no claim.",
   "sha": "59e1142c",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-009",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A note on residue-numbering convention pointing to a supplementary sequence figure, asserting nothing about the sensor.",
   "sha": "f4fd8433"
  },
  {
   "uid": "results-023",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A bare figure title for the annotated sequence supplement, carrying no finding of its own.",
   "sha": "69066e07"
  },
  {
   "uid": "results-037",
   "verdict": "covered",
   "claim": "mutagenesis-3947-variants-screened",
   "why": "The claim that 3,947 variants were generated from 39 targeted sites accounts for this breakdown of where those 39 sites lie.",
   "sha": "162ae33f",
   "claim_sha": "cf00e2ea"
  },
  {
   "uid": "results-059",
   "verdict": "covered",
   "claim": "igabasnfr2-fourfold-sensitivity-gain",
   "why": "This is the 4.1-fold peak dF/F improvement the claim asserts, reported here with its statistics and the accompanying SNR gain.",
   "sha": "22d0fe78",
   "claim_sha": "9b8a5958"
  },
  {
   "uid": "results-060",
   "verdict": "covered",
   "claim": "igabasnfr2-kinetics-rise-decay",
   "why": "The claim states exactly this pairing of a faster rise and a slower decay for iGABASnFR2 relative to iGABASnFR1.",
   "sha": "1f1b8c65",
   "claim_sha": "70dcfeab"
  },
  {
   "uid": "results-061",
   "verdict": "gap",
   "claim": null,
   "why": "The tree's only claim about iGABASnFR2n covers its screening dF/F and responsive-pixel count, not its evoked-release performance in neurons (3.3-fold peak dF/F, 40% higher SNR).",
   "sha": "af31b87f",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-066",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the traces and error bars represent.",
   "sha": "077e6533"
  },
  {
   "uid": "results-067",
   "verdict": "gap",
   "claim": null,
   "why": "The kinetics claim covers rise and decay at 10 action potentials; the single-AP rise-time comparison shown in this panel is stated nowhere in the tree.",
   "sha": "bd80028a",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-084",
   "verdict": "gap",
   "claim": null,
   "why": "No claim states that the F101L hinge mutation of iGABASnFR1 raised binding affinity tenfold.",
   "sha": "2eb9bf42",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-086",
   "verdict": "gap",
   "claim": null,
   "why": "The structural claims cover the deposition and the rigidity of cpGFP on binding, but not the identity of the residues that form the GABA binding site.",
   "sha": "5f43fa32",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-091",
   "verdict": "gap",
   "claim": null,
   "why": "The proposed hydrogen-bonding role of the L178gfpS mutation in enhancing the fluorescence change is a mechanistic interpretation no claim carries.",
   "sha": "2aded4dc",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-103",
   "verdict": "gap",
   "claim": null,
   "why": "The affinity claim is about on-cell EC50; the purified-protein result that iGABASnFR2 has a smaller dynamic range than iGABASnFR1 despite higher solution affinity appears in no claim.",
   "sha": "f144e398",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-113",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the fitted lines and error bars represent.",
   "sha": "22ac2311"
  },
  {
   "uid": "results-122",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the fitted lines represent and how many replicates they average.",
   "sha": "4345706b"
  },
  {
   "uid": "results-128",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A statement of replicate count for the titrations, not a result.",
   "sha": "3167018a"
  },
  {
   "uid": "results-130",
   "verdict": "covered",
   "claim": "igabasnfr2-gaba-selective-specificity",
   "why": "This describes the competition titrations against related compounds at 1 mM that the selectivity claim reports as showing no interference.",
   "sha": "8990929a",
   "claim_sha": "2233bfaa"
  },
  {
   "uid": "results-136",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the plotted points and error bars represent.",
   "sha": "30fc6a04"
  },
  {
   "uid": "results-144",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A pure cross-reference to Table 1.",
   "sha": "c1690d0d"
  },
  {
   "uid": "results-147",
   "verdict": "gap",
   "claim": null,
   "why": "This table is the only place the purified-protein photophysics appear - extinction coefficients (iGABASnFR2 roughly double iGABASnFR1's), quantum yields, fluorescence lifetimes and peak wavelengths - and no claim states any of them.",
   "sha": "e04c6071",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-152",
   "verdict": "gap",
   "claim": null,
   "why": "The retina claim asserts that direction-selective GABA release was demonstrated, but no claim states the centrifugal-versus-centripetal hypothesis being tested.",
   "sha": "182a4bb1",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-153",
   "verdict": "gap",
   "claim": null,
   "why": "The relay of direction-selective inhibition to DSGCs through asymmetric connections is background from prior work that no claim in the tree carries.",
   "sha": "2f353163",
   "tree": "b6bc662a"
  },
  {
   "uid": "results-160",
   "verdict": "covered",
   "claim": "igabasnfr2-retina-direction-selectivity",
   "why": "The claim's comparison of response reliability between the two sensors accounts for these amplitude and reliability distributions from iGABASnFR-expressing SACs.",
   "sha": "c0e1f4d8",
   "claim_sha": "3aa1c28a"
  },
  {
   "uid": "results-161",
   "verdict": "covered",
   "claim": "igabasnfr2-retina-direction-selectivity",
   "why": "The matching iGABASnFR2 distributions are the other half of the sensor comparison the claim makes.",
   "sha": "18831152",
   "claim_sha": "3aa1c28a"
  },
  {
   "uid": "results-164",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the line and shading represent.",
   "sha": "39e35e3c"
  },
  {
   "uid": "results-165",
   "verdict": "covered",
   "claim": "igabasnfr2-retina-direction-selectivity",
   "why": "The claim asserts significantly higher SNR for iGABASnFR2 in retina, which is what this comparison tests.",
   "sha": "f62aa92f",
   "claim_sha": "3aa1c28a"
  },
  {
   "uid": "results-166",
   "verdict": "covered",
   "claim": "igabasnfr2-retina-direction-selectivity",
   "why": "The claim that iGABASnFR2 resolves direction selectivity where iGABASnFR1 cannot accounts for this circular-variance comparison.",
   "sha": "0d12f294",
   "claim_sha": "3aa1c28a"
  },
  {
   "uid": "captions-004",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A note on residue-numbering convention pointing to a supplementary sequence figure, asserting nothing about the sensor.",
   "sha": "f4fd8433"
  },
  {
   "uid": "captions-018",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A bare figure title for the annotated sequence supplement, carrying no finding of its own.",
   "sha": "1e7abca1"
  },
  {
   "uid": "captions-029",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the traces and error bars represent.",
   "sha": "077e6533"
  },
  {
   "uid": "captions-030",
   "verdict": "gap",
   "claim": null,
   "why": "The kinetics claim covers rise and decay at 10 action potentials; the single-AP rise-time comparison shown in this panel is stated nowhere in the tree.",
   "sha": "bd80028a",
   "tree": "b6bc662a"
  },
  {
   "uid": "captions-044",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the fitted lines and error bars represent.",
   "sha": "22ac2311"
  },
  {
   "uid": "captions-053",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the fitted lines represent and how many replicates they average.",
   "sha": "4345706b"
  },
  {
   "uid": "captions-060",
   "verdict": "covered",
   "claim": "igabasnfr2-gaba-selective-specificity",
   "why": "This describes the competition titrations against related compounds at 1 mM that the selectivity claim reports as showing no interference.",
   "sha": "8990929a",
   "claim_sha": "2233bfaa"
  },
  {
   "uid": "captions-065",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the plotted points and error bars represent.",
   "sha": "30fc6a04"
  },
  {
   "uid": "captions-072",
   "verdict": "covered",
   "claim": "igabasnfr2-retina-direction-selectivity",
   "why": "The claim's comparison of response reliability between the two sensors accounts for these amplitude and reliability distributions from iGABASnFR-expressing SACs.",
   "sha": "c0e1f4d8",
   "claim_sha": "3aa1c28a"
  },
  {
   "uid": "captions-073",
   "verdict": "covered",
   "claim": "igabasnfr2-retina-direction-selectivity",
   "why": "The matching iGABASnFR2 distributions are the other half of the sensor comparison the claim makes.",
   "sha": "18831152",
   "claim_sha": "3aa1c28a"
  },
  {
   "uid": "captions-076",
   "verdict": "not-an-assertion",
   "claim": null,
   "why": "A graphical-encoding note on what the line and shading represent.",
   "sha": "39e35e3c"
  },
  {
   "uid": "captions-077",
   "verdict": "covered",
   "claim": "igabasnfr2-retina-direction-selectivity",
   "why": "The claim asserts significantly higher SNR for iGABASnFR2 in retina, which is what this comparison tests.",
   "sha": "f62aa92f",
   "claim_sha": "3aa1c28a"
  },
  {
   "uid": "captions-078",
   "verdict": "covered",
   "claim": "igabasnfr2-retina-direction-selectivity",
   "why": "The claim that iGABASnFR2 resolves direction selectivity where iGABASnFR1 cannot accounts for this circular-variance comparison.",
   "sha": "0d12f294",
   "claim_sha": "3aa1c28a"
  },
  {
   "uid": "tables-001",
   "verdict": "gap",
   "claim": null,
   "why": "This table is the only place the purified-protein photophysics appear - extinction coefficients (iGABASnFR2 roughly double iGABASnFR1's), quantum yields, fluorescence lifetimes and peak wavelengths - and no claim states any of them.",
   "sha": "70881f81",
   "tree": "b6bc662a"
  }
 ]
}