Edge inference

blocked upstream · v10 provisional awaiting approval

Which claims depend on which?

for Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions · this layer across all papers · json

Provisional

This layer needs a corpus-scope decision that has not been ruled on yet, so what it produces would change if the decision changed. It waits on claim-format, relation-vocab.

Awaiting approval

Waiting for approval. That is a statement about the record, not about whether anyone has read this: people read the corpus without stamping what they read, and only a stamp leaves a trace. Approval is an operation on a version, not a step of its own — it is recorded against the version it was granted to, so running this layer again does not carry it forward.

What it produced78 edges

Read from runs/gadeke-2026-guilt-insula/edge-inference.output.json · 21 KB. model supplied:runs/gadeke-2026-guilt-insula/edge-inference.answer.v10.json

#	source	target	relation	why
1	responsibility-social-choice-yields-low	responsibility-outcomes-generates-guilt-participant	entails	the guilt hypothesis deductively implies the happiness prediction (results-119)
2	responsibility-social-choice-yields-low	responsibility-partner-outcomes-influences-participant	entails	if responsibility for outcomes generates guilt, a model with social_pRPE should fit happiness better
3	anterior-insula-neural-substrate-guilt	anterior-insula-tracks-guilt-insula	entails	the insula-as-guilt-substrate hypothesis implies insula BOLD is higher Social>Partner with a Social:LowOutcome interaction (results-124)
4	functional-connectivity-between-guilt-responsibility-related	connectivity-between-guilt-responsibility-related-outcome-ph	entails	the connectivity hypothesis implies a seed-to-voxel PPI reveals a prefrontal Condition-by-Choice interaction
5	neural-substrate-tracks-participant-responsibility	neural-substrate-tracks-participant-responsibility-2	entails	the responsibility-tracking hypothesis implies outcome-sensitive regions respond more to partner pRPE from participant choices
6	when-partner-received-low-lottery	responsibility-outcomes-generates-guilt-participant	tests	the partner-outcome x decision-maker interaction tests the happiness prediction
7	when-partner-received-low-lottery	responsibility-outcomes-generates-guilt-participant	confirms	the interaction was significant in both studies: happiness lower after low partner outcomes from own choice
8	insula-rois-responded-more-low	anterior-insula-tracks-guilt-insula	tests	the insula ROI Social>Partner low-outcome response tests the insula BOLD prediction (results-127)
9	insula-rois-responded-more-low	anterior-insula-tracks-guilt-insula	confirms	insula ROIs responded more to low partner outcomes in Social, mirroring the guilt effect
10	mass-univariate-voxel-wise-analysis-found-small	anterior-insula-tracks-guilt-insula	tests	the mass-univariate voxel-wise search tests the insula BOLD prediction (results-129)
11	mass-univariate-voxel-wise-analysis-found-small	anterior-insula-tracks-guilt-insula	confirms	a small left anterior insula cluster survived small-volume FWE correction (p = 0.024)
12	likelihood-ratio-test-showed-responsibility	responsibility-partner-outcomes-influences-participant	tests	the likelihood-ratio comparison tests whether the Responsibility model (with social_pRPE) fits best
13	likelihood-ratio-test-showed-responsibility	responsibility-partner-outcomes-influences-participant	confirms	the Responsibility model fitted better than all other models in both studies
14	partner-reward-prediction-errors-resulting	responsibility-partner-outcomes-influences-participant	tests	the social_pRPE weight tests the prediction that partner pRPE from own choices contributes
15	partner-reward-prediction-errors-resulting	responsibility-partner-outcomes-influences-participant	confirms	social_pRPE weights were reliably greater than zero in both studies
16	one-cluster-left-sts-responded	neural-substrate-tracks-participant-responsibility-2	tests	the left-STS search tests the partner-pRPE-from-own-choice prediction (fig4h)
17	one-cluster-left-sts-responded	neural-substrate-tracks-participant-responsibility-2	confirms	one left-STS cluster responded more to partner pRPE from participant than partner choices (pFWE = 0.022)
18	functional-connectivity-between-left-anterior	connectivity-between-guilt-responsibility-related-outcome-ph	tests	the insula-seed PPI tests the prefrontal Condition-by-Choice interaction prediction (results-142)
19	functional-connectivity-between-left-anterior	connectivity-between-guilt-responsibility-related-outcome-ph	confirms	a right-IFG cluster's insula connectivity varied with condition and choice and survived FWE correction
20	when-partner-received-low-lottery	responsibility-social-choice-yields-low	supports	the behavioural guilt effect is evidence for the guilt hypothesis
21	likelihood-ratio-test-showed-responsibility	responsibility-social-choice-yields-low	supports	the Responsibility model's superior fit supports the responsibility/guilt account
22	partner-reward-prediction-errors-resulting	responsibility-social-choice-yields-low	supports	a positive social_pRPE weight supports that partner outcomes from own choices affect happiness
23	insula-rois-responded-more-low	anterior-insula-neural-substrate-guilt	supports	the insula guilt-tracking response supports the insula-as-substrate hypothesis
24	one-cluster-left-sts-responded	neural-substrate-tracks-participant-responsibility	supports	the left-STS responsibility signal supports the responsibility-tracking hypothesis
25	functional-connectivity-between-left-anterior	functional-connectivity-between-guilt-responsibility-related	supports	condition/choice-dependent insula connectivity supports the connectivity hypothesis
26	prior-literature-documents-association-between	anterior-insula-neural-substrate-guilt	supports	the prior insula-guilt association is why the insula was hypothesised as the substrate
27	prior-functional-connectivity-work-shown	functional-connectivity-between-guilt-responsibility-related	supports	prior functional-connectivity work motivates the connectivity hypothesis
28	rutledge-colleagues-established-changes-momentary	likelihood-ratio-test-showed-responsibility	supports	Rutledge's momentary-happiness framework grounds the fitted happiness models
29	participant-momentary-happiness-varied-rewards	likelihood-ratio-test-showed-responsibility	supports	happiness varying with participant rewards grounds fitting reward-based happiness models
30	participant-momentary-happiness-varied-rewards-2	likelihood-ratio-test-showed-responsibility	supports	happiness varying with partner rewards grounds the partner-RPE terms of the models
31	participants-own-reward-prediction-errors	likelihood-ratio-test-showed-responsibility	supports	the ordering of RPE weights corroborates the Responsibility model structure
32	when-partner-received-low-lottery	both-studies-participants-felt-worse	supports	the guilt interaction is the evidence for the synthesis that participants felt worse from their own choices
33	risk-premiums-not-differ-between	participants-showed-very-similar-risk	supports	equal risk premiums across conditions support the similar-risk-preferences synthesis
34	participants-slightly-more-risk-averse	participants-showed-very-similar-risk	supports	only a slight Study-1 risk-aversion difference supports the 'similar with a tendency' synthesis
35	no-significant-interaction-between-difference	participants-showed-very-similar-risk	supports	no EV-difference-by-condition interaction supports similar preferences across conditions
36	left-superior-temporal-sulcus-cluster	one-cluster-left-sts-responded	supports	the STS response across both sessions corroborates the left-STS responsibility result
37	dot-products-between-individual-neural	insula-rois-responded-more-low	validates	positive dot products with the published Yu GRBS give convergent validity to the insula guilt response (results-152)
38	manipulation-check-bilateral-ventral-striatum	model-based-glm-entered-best-fitting-computational	validates	the ventral-striatum manipulation check confirms the model-based GLM recovers reward signals
39	guilt-effect-occurred-whether-participant	when-partner-received-low-lottery	validates	the guilt effect held whether the participant's own outcome was high or low, ruling out own-outcome confounds
40	responsibility-choices-not-influence-happiness	when-partner-received-low-lottery	validates	no responsibility effect after high partner outcomes shows the effect is specific to low outcomes (guilt)
41	risk-aversion-parameter-not-differ-between	momentary-happiness-modelled-five-computational	validates	equal risk-aversion across gain/loss trials justifies pooling in the models
42	pre-task-icebreaker-succeeded-establishing-positive	when-partner-received-low-lottery	validates	the icebreaker established a positive partner attitude, warranting that the effect reflects guilt toward a valued partner
43	lower-happiness-when-participant-decision-maker	participant-happiness-lower-when-participant	interprets	responsibility aversion is offered as a reading of the agency effect (results-073)
44	behavioural-guilt-effect-larger-happiness	when-partner-received-low-lottery	interprets	'simple guilt' is the interpretive reading of the behavioural guilt interaction (results-080)
45	authors-suggest-left-sts-region	one-cluster-left-sts-responded	interprets	the STS-tracks-partner-outcomes reading interprets the left-STS result (results-138)
46	connectivity-between-left-anterior-insula	functional-connectivity-between-left-anterior	interprets	the prefrontal-sensitivity reading interprets the insula-IFG connectivity result (abstract-009)
47	during-outcome-phase-responses-low	insula-rois-responded-more-low	part-of	the outcome-phase table is one measure of the insula guilt response the whole result states
48	difference-response-between-low-high	insula-rois-responded-more-low	part-of	the low-minus-high difference is one measure of the same insula guilt response
49	when-partner-received-low-lottery	linear-mixed-model-containing-all	requires	the reported guilt interaction depends on Model 5's LMM being the warranted model
50	one-cluster-left-sts-responded	model-based-glm-entered-best-fitting-computational	requires	the STS responsibility result depends on the model-based GLM2 regressors
51	likelihood-ratio-test-showed-responsibility	model-selection-among-happiness-models	requires	the model-comparison result depends on the likelihood-ratio selection procedure
52	insula-rois-responded-more-low	during-receipt-lottery-versus-safe	requires	the insula guilt ROI depends on the outcome-responsive localizer regions
53	hold-partner-behaviour-constant-across	when-partner-received-low-lottery	enables-method	simulating the partner's choices holds behaviour constant, making the guilt comparison possible
54	model-selection-among-happiness-models	likelihood-ratio-test-showed-responsibility	enables-method	the likelihood-ratio selection method makes the model-comparison result interpretable
55	parameter-recovery-procedure-synthetic-data-generated	responsibility-redux-model-incorporating-expected	enables-method	parameter recovery establishes the model estimates are stable enough to trust the fit
56	findings-rest-two-samples-healthy	when-partner-received-low-lottery	scopes	the guilt effect is bounded to two samples of healthy adults
57	each-trial-participants-chose-between	when-partner-received-low-lottery	scopes	the effect is bounded to the three-condition safe/risky choice paradigm
58	study-reproduced-study-design-inside	insula-rois-responded-more-low	scopes	the neural results are bounded to the fMRI reproduction of the design in Study 2
59	participant-happiness-lower-when-participant	when-partner-received-low-lottery	dissociates-with	two effects both present and distinct: agency lowers happiness regardless of outcome, guilt only after the partner's loss
60	dot-products-between-individual-neural	individual-grbs-dot-product-values-not	in-tension-with	the neural guilt response matches the published Yu/Koban signature at the group level (60), yet individual signature scores do not track individual behavioural guilt (61); both stand and the null boun…
61	only-precuneus-tpj-showed-positive	decisions-social-compared-solo-condition	part-of	the precuneus/TPJ Risky-Safe analysis (fig4c) is one component of the Social>Solo cluster result (fig4b)
62	decisions-social-compared-solo-condition	each-trial-participants-chose-between	requires	the Social>Solo contrast requires the three-condition (Solo/Social/Partner) choice paradigm to have been run
63	responsibility-model-yielded-higher-values	likelihood-ratio-test-showed-responsibility	supports	the Responsibility model's higher R2 (table1) corroborates the likelihood-ratio verdict that it fits best
64	responsibility-model-yielded-higher-values	momentary-happiness-modelled-five-computational	requires	the R2 model comparison (table1) requires the five happiness models to have been fitted
65	among-computational-models-fitted-momentary	momentary-happiness-modelled-five-computational	requires	the Responsibility Redux AIC ranking (table1) requires the five happiness models to have been fitted
66	responsibility-redux-model-incorporating-expected	momentary-happiness-modelled-five-computational	requires	the Responsibility Redux model's predictions (fig3c,fig3g) require that model to have been fitted
67	parameter-recovery-procedure-synthetic-data-generated	responsibility-redux-model-incorporating-expected	validates	the parameter-recovery procedure (fig3s1) verifies the Responsibility Redux estimates are stable, strengthening the fit
68	participants-chose-risky-option-lottery	participants-showed-very-similar-risk	supports	the Solo>Social lottery-choice difference (fig2a,fig2d) is one of the risk-preference results the synthesis draws together
69	participants-chose-risky-option-lottery	each-trial-participants-chose-between	requires	the Solo/Social choice-proportion result requires the three-condition choice paradigm to have been run
70	mixed-effects-regressions-choices-social-condition	participants-chose-risky-option-lottery	part-of	the mixed-effects choice regression (app1table1) is the formal analysis behind the reported Solo/Social choice difference
71	linear-mixed-model-containing-all	when-partner-received-low-lottery	validates	Model 5 with all two-way interactions fits best (app1table2), validating that the reported guilt interaction is drawn from the warranted model
72	both-studies-participants-felt-worse	responsibility-social-choice-yields-low	supports	the across-both-studies guilt effect is evidence for the responsibility-guilt hypothesis; the edge task wrote edges into the synthesis and none out (#53)
73	left-ifg-cluster-showed-opposite	connectivity-between-left-anterior-insula	qualifies	the uncorrected left-IFG cluster showed the opposite connectivity pattern, so it bounds the connectivity finding rather than confirming it (#53)
74	responsibility-outcomes-generates-guilt-participant	responsibility-social-choice-yields-low	derived-from	reciprocal of entails (responsibility-social-choice-yields-low → responsibility-outcomes-generates-guilt-participant)
75	responsibility-partner-outcomes-influences-participant	responsibility-social-choice-yields-low	derived-from	reciprocal of entails (responsibility-social-choice-yields-low → responsibility-partner-outcomes-influences-participant)
76	anterior-insula-tracks-guilt-insula	anterior-insula-neural-substrate-guilt	derived-from	reciprocal of entails (anterior-insula-neural-substrate-guilt → anterior-insula-tracks-guilt-insula)
77	connectivity-between-guilt-responsibility-related-outcome-ph	functional-connectivity-between-guilt-responsibility-related	derived-from	reciprocal of entails (functional-connectivity-between-guilt-responsibility-related → connectivity-between-guilt-responsibility-related-outcome-ph)
78	neural-substrate-tracks-participant-responsibility-2	neural-substrate-tracks-participant-responsibility	derived-from	reciprocal of entails (neural-substrate-tracks-participant-responsibility → neural-substrate-tracks-participant-responsibility-2)

How it is defined

A model answers this layer, so the prompt is the layer. It is reproduced below from the committed file, and it is a declared input — editing it makes every run that used it stale.

extract/prompts/edge-inference.mdthe prompt it runs undernot in the repository

The declaration names this path and the repository does not have it. An input that does not exist hashes to nothing, so it cannot make a run stale — the layer is declared to depend on something it is not in fact tracking.

extract/prompts/contract/vocabulary.mdthe prompt it runs undernot in the repository

Artifacts

runs/gadeke-2026-guilt-insula/edge-inference.output.json

Versions

From the run ledger. There is no changelog beside it to keep in step.

v10 · 2026-09-14 · Claude Opus (subagent, via --answer)

syntheses point outward; qualifies for unconfirmed results (#53)

cd extract && python3 -m claim_graphs.cli edge-inference --paper gadeke-2026-guilt-insula --answer runs/gadeke-2026-guilt-insula/edge-inference.answer.v10.json
v9 · 2026-09-13 · Claude Opus (subagent, via --answer)

edge completion pass

cd extract && python3 -m elife_extract.cli edge-inference --paper gadeke-2026-guilt-insula --answer runs/gadeke-2026-guilt-insula/edge-inference.answer.v9.json
v8 · 2026-09-13 · Claude Opus (subagent, via --answer)

tensions and unsupported parts per #125 ruling

cd extract && python3 -m elife_extract.cli edge-inference --paper gadeke-2026-guilt-insula --answer runs/gadeke-2026-guilt-insula/edge-inference.answer.v8.json
v6 · 2026-09-13 · Claude Opus (subagent, via --answer)

outcomes per #28 ruling

cd extract && python3 -m elife_extract.cli edge-inference --paper gadeke-2026-guilt-insula --answer runs/gadeke-2026-guilt-insula/edge-inference.answer.v6.json
v5 · 2026-09-12 · Claude Opus 4.8 (1M context) (subagent, via --answer)

edge-inference under the current chain (#96)

cd extract && python3 -m elife_extract.cli edge-inference --paper gadeke-2026-guilt-insula --answer runs/gadeke-2026-guilt-insula/edge-inference.answer.v5.json
v4 · 2026-09-11 · Claude Opus 4.8 (1M context) (subagent, via --answer)

edge inference on the contract (#83)

cd extract && python3 -m elife_extract.cli edge-inference --paper gadeke-2026-guilt-insula --answer runs/gadeke-2026-guilt-insula/edge-inference.answer.v4.json
v3 · 2026-09-11 · claude-opus-5 (subagent, via --answer)

first run under the prompt contract (#56 item 4); Opus 5 subagents for every layer; answered through --dump-prompt/--answer, not the configured backend

cd extract && python3 -m elife_extract.cli edge-inference --paper gadeke-2026-guilt-insula --answer runs/gadeke-2026-guilt-insula/edge-inference.answer.v3.json
v2 · 2026-09-11 · claude-opus-5 (subagent, via --answer)

first run under the prompt contract (#56 item 4); Sonnet 5 subagents read, Opus 5 subagents reconciled, reviewed and inferred edges; answered through --dump-prompt/--answer, not the configured backend

cd extract && python3 -m elife_extract.cli edge-inference --paper gadeke-2026-guilt-insula --answer runs/gadeke-2026-guilt-insula/edge-inference.answer.v2.json
v1 · 2026-09-10 · claude-opus-5 (agent, not the configured backend) backfilled from the artifact

backfilled from runs/manifest.json

This layer across the corpus

Across the corpus

9 not run · 1 blocked upstream·a paper links to its own cell, where this layer's output for it is rendered

Paper	State	Version	Last run	Output	Cell
A three-dimensional immunofluorescence atlas of the …	not run	—	—	—	json
Distinct representational properties of cues and con…	not run	—	—	—	json
Computational modelling identifies key determinants …	not run	—	—	—	json
Contributions of insula and superior temporal sulcus…syntheses point outward; qualifies for unconfirmed results (#53)	blocked upstream	v10	2026-09-14	edge-inference.output.json	json
Spatially targeted inhibitory rhythms differentially…	not run	—	—	—	json
Feedback of peripheral saccade targets to early fove…	not run	—	—	—	json
iGABASnFR2 is an improved genetically encoded protei…	not run	—	—	—	json
A deep learning pipeline for mapping in situ network…	not run	—	—	—	json
Self-association enhances early attentional selectio…	not run	—	—	—	json
Impaired excitability of fast-spiking neurons in a n…	not run	—	—	—	json

Inputs and outputs

Reads, besides its dependencies: extract/prompts/edge-inference.md · declared, and not in the repository — it hashes to nothing, so it cannot make a run stale
extract/prompts/contract/vocabulary.md · declared, and not in the repository — it hashes to nothing, so it cannot make a run stale
Produces: runs/{paper}/edge-inference.output.json

One per paper — the table above links each one that exists.
Views: graph — on the paper page, as the claim graph
table — rendered above, over the 78 edges in the artifact
comparison — on the cell page, two versions aligned by the matcher, wherever the ledger holds more than one

Running it

The command comes from the declaration, so this text and what actually runs cannot diverge. pipeline.py run also runs the unmet dependencies first.

python3 scripts/pipeline.py run <paper> edge-inference

Underneath, that runs cd extract && python3 -m claim_graphs.cli edge-inference --paper {paper}.