Coverage

blocked upstream · v5 provisional awaiting approval

What does the paper assert that no claim represents?

for A deep learning pipeline for mapping in situ network-level neurovascular coupling in multi-photon fluorescence microscopy · this layer across all papers · json

Provisional

This layer needs a corpus-scope decision that has not been ruled on yet, so what it produces would change if the decision changed. It waits on claim-format, relation-vocab.

Awaiting approval

Waiting for approval. That is a statement about the record, not about whether anyone has read this: people read the corpus without stamping what they read, and only a stamp leaves a trace. Approval is an operation on a version, not a step of its own — it is recorded against the version it was granted to, so running this layer again does not carry it forward.

What it produced40 spans.orphans

Read from coverage/rozak-2026-neurovascular-dl.json · 14 KB. claims 24panels.pct 16.3statistics.total 10statistics.pct 30spans.segmented 302spans.obligations 83spans.textual 219spans.accounted 43spans.pct 51.8

# uidsectiontextstatspanels
1 results-010 results The Dice, precision, recall, mean surface distance, and HD95 distance for the vascular ( A ) and neuron ( B ) channels. [] ["fig3a","fig3b"]
2 results-014 results ( A ) Raw images of the vascular channel with the neuron channel subtracted to facilitate vessel visualization. [] ["fig4a"]
3 results-017 results ( B ) Ground truth segmentation masks for the vasculature were generated by a rater who utilized ilastik-assisted manual segmentation. [] ["fig4b"]
4 results-018 results ( C ) Ilastik predictions generated via a random forest model. [] ["fig4c"]
5 results-019 results ( D ) Binary segmentation masks generated by an ensemble of 3D UNet models. [] ["fig4d"]
6 results-020 results ( E ) Binary segmentation masks generated by an ensemble of 3D UNETR models. [] ["fig4e"]
7 results-029 results Across > 100,000 simulations, the fit of the estimated radius following rescaling against the simulated radius had an R 2 value of 0.68. Figure 5B presents a heatmap of the estimated radius post-scali… [] ["fig5b"]
8 results-032 results ( A ) An image in the plane orthogonal to the local tangent to a capillary with the detected boundary (in blue) and with the estimated radius of 2.28 μm. [] ["fig5a"]
9 results-034 results ( B ) The plot shows correspondence between the estimated radius following scaling and the simulated level of scaling. [] ["fig5b"]
10 results-035 results ( C ) An image in the plane orthogonal to the local tangent of a capillary with the detected boundary (in blue) and with the estimated radius of 3.65 μm. [] ["fig5c"]
11 results-037 results ( D ) The estimated % change in the vessel’s radius after the addition of varying levels of Gaussian noise, demonstrating the robustness of the radius estimated to noise. [] ["fig5d"]
12 results-043 results As the amount of averaging increased, the uncertainty on the diameter of the beads decreased, and our estimate of the bead’s diameter converged upon the manufacturer’s Coulter counter-based specificat… [] ["table1"]
13 results-044 results Table 1. Bead diameter estimates. [] ["table1"]
14 results-049 results To highlight the ability of the pipeline to detect vessels that significantly change their radius after stimulation, Figure 6A shows the standard deviation of the average radii on each vessel segment … [] ["fig6a"]
15 results-051 results We examined the average change in the vascular radius of each vessel segment after vs. before photostimulation ( Figure 6B ), with even finer spatial patterns detected by analyzing the vertex-wise rad… [] ["fig6b","fig6c"]
16 results-052 results The vascular diameter changes were related to the distance from the vessel’s surface to the closest labeled pyramidal neuron at each vertex of the centerline ( Figure 6D ). [] ["fig6d"]
17 results-057 results Table 2. S1FL vascular network morphological properties. [] ["table2"]
18 results-059 results ( A ) Baseline variability in vessel diameter estimated by the standard deviation of each vessel’s mean radius across baseline time frames. [] ["table2a"]
19 results-060 results ( B ) Mean change in the vessel radius induced by optogenetic stimulation. [] ["table2b"]
20 results-061 results ( C ) Mean change in the vertexwise radius, allowing the visualization of heterogeneity of radius changes within each vessel. [] ["table2c"]
21 results-062 results ( D ) Distance from each vertex to the closest pyramidal neuron. [] ["table2d"]
22 results-067 results ( B ) Estimates of the vertex-wise radius obtained along each of the three vessels’ centrelines, before and after stimulation. [] ["fig7b"]
23 results-068 results ( C ) Vertex-wise radii changes in response to optogenetic stimulation. [] ["fig7c"]
24 results-069 results ( D ). [] ["fig7d"]
25 results-074 results The morphometric properties of the responders, under different stimulation conditions, are listed in Table 3 . [] ["table3"]
26 results-081 results Table 3. Details of responder (Δ R >2 * σR baseline ) vessels. [] ["table3"]
27 results-084 results ( C ) Probability density function of constrictions and dilations for the 4.3 mW/mm 2 photostimulation. [] ["table3c"]
28 results-085 results ( D ) Changes to capillary radii are displayed in relation to the closest pyramidal neurons. [] ["table3d"]
29 results-087 results ( E ) Mean cortical depth of responding capillaries showed a tendency for dilators to be closer to the surface and for constrictors to be deeper in the tissue. [] ["table3e"]
30 results-094 results For constrictions, 458 nm photostimulations led to –1.39±1.51 μm radius changes with 1.1 m W m m 2 \begin{document}$\frac{mW}{mm^{2}}$\end{document} and –1.20±1.13 μm radius changes with 4.3 m W m m 2… ["p=4.4e-3","p=0.02"] []
31 results-102 results ( A ) Graph representation of a vascular network of 425 vascular segments from a single image stack. [] ["fig9a"]
32 results-108 results There was a significant increase (p=0.03) in the capillary network efficiency post 458 nm light at 4.3 mW/mm 2 , when compared to that following the control green illumination. ["p=0.03"] []
33 discussion-063 discussion Example slices of the segmentation results are shown in Appendix 1—figure 10 . [] ["fig10"]
34 discussion-068 discussion Visualizations of the two graphs are shown in Appendix 1—figure 11 . [] ["fig11"]
35 discussion-077 discussion Our vascular segmentation model generalized well to C57BL/6J mouse and Fischer rat data, as well as to Thy1-ChR2 light-sheet fluorescence microscopy images gathered on an UltraMicroscope Blaze lightsh… [] ["fig12","table3"]
36 discussion-085 discussion Additionally, alternative definitions of responding vessels may be useful depending on the end goal of a study (e.g. selecting a threshold for the radius change based on a percentage change from the b… [] ["fig14"]
37 captions-003 captions The emitted light passes through the objective, is reflected off the FV30-NDM690 dichroic mirror, and passes through a 650 nm barrier filter before reaching a 570 nm long pass filter (LPF) separating … [] ["fig2"]
38 captions-061 captions There was a significant increase (p=0.03) in the capillary network efficiency post 458 nm light at 4.3 mW/mm 2 , when compared to that following the control green illumination. ["p=0.03"] []
39 tables-001 tables Table 1. Bead diameter estimates. [] ["table1"]
40 tables-002 tables Number of orthogonal planes Number of spokes per plane Mean diameter estimate (μm) 1 3 7.54±0.68 2 4 7.44±0.51 4 12 7.34±0.38 10 36 7.34±0.32 Table 2. S1FL vascular network morphological properties. [] ["table2"]

Artifacts

Versions

From the run ledger. There is no changelog beside it to keep in step.

  1. v5 · 2026-09-13 · scripts/pipeline.py run

    ran via scripts/pipeline.py

    cd extract && python3 -m elife_extract.cli coverage --paper rozak-2026-neurovascular-dl --json ../coverage/rozak-2026-neurovascular-dl.json

  2. v4 · 2026-09-13 · scripts/pipeline.py run

    ran via scripts/pipeline.py

    cd extract && python3 -m elife_extract.cli coverage --paper rozak-2026-neurovascular-dl --json ../coverage/rozak-2026-neurovascular-dl.json

  3. v3 · 2026-09-12 · scripts/pipeline.py run

    re-run after prepare v2

    cd extract && python3 -m elife_extract.cli coverage --paper rozak-2026-neurovascular-dl --json ../coverage/rozak-2026-neurovascular-dl.json

  4. v2 · 2026-09-11 · scripts/pipeline.py run

    coverage for the nine papers that had none

    cd extract && python3 -m elife_extract.cli coverage --paper rozak-2026-neurovascular-dl --json ../coverage/rozak-2026-neurovascular-dl.json

  5. v1 · 2026-09-11 · scripts/pipeline.py run

    ran via scripts/pipeline.py

    cd extract && python3 -m elife_extract.cli coverage --doi 10.7554/eLife.95525 --paper-slug rozak-2026-neurovascular-dl --claims-dir ../claims/rozak-2026-neurovascular-dl --json ../coverage/rozak-2026-neurovascular-dl.json

This layer across the corpus

Across the corpus

4 blocked upstream · 6 stale·a paper links to its own cell, where this layer's output for it is rendered

Inputs and outputs

Produces
  • coverage/{paper}.json

One per paper — the table above links each one that exists.

Views
  • document — declared, and this artifact is not the shape this view needs
  • table — rendered above, over the 128 spans.orphans in the artifact

Running it

The command comes from the declaration, so this text and what actually runs cannot diverge. pipeline.py run also runs the unmet dependencies first.

python3 scripts/pipeline.py run <paper> coverage

Underneath, that runs cd extract && python3 -m claim_graphs.cli coverage --paper {paper} --json ../coverage/{paper}.json.